Baclofen (Lioresal)
General information. Baclofen ( also Lioresal) without prescription represents itself a medicine that helps to treat anxiety disorders – a group of syndromes that one might notice by excessive anxiety, intense fear, internal stress and / or physical symptoms in the absence of the actual situation of threat and also helps to treat alcoholism. About 50% of individuals in the society experience many episodes anxiety disorders during life. Pharmacoeconomic studies show that one-third of all health care costs in general goes one treating mental illness or anxiety and alcoholism. At the same time, a large group of patients do not go to the doctor and remain untreated. Usually, anxiety or some slight symptoms of anxiety are the basis for a more severe psychopathological syndrome. One can order Baclofen (Lioresal) at online pharmacy.
Pharmacotherapy of anxiety disorders remains an area of active study and the main issue is the choice of medication for treatment of anxiety.
The main advantage of Baclofen (Lioresal) buy over other medications is the rapidity of development of clinical effect. According to the multi-center study, 76% cases of treatment with the drug were well tolerated regardless of the dose. By the end of the 2nd week of treatment most symptoms are mild and loose both objective and subjective significance.
Indications. Baclofen (Lioresal) order shows high anxiolytic effect in placebo-controlled studies in patients with alcoholism, phobia, panic disorders and possible anxiety symptoms associated with major depression.
Dosage. For most patients Baclofen (Lioresal) online is prescribed as follows: an initial dose of 5 mg / day for 1 week, followed by changing to 10 mg / day if the patient has a good tolerability.
Objectively, all indicators of psychometric tests were significantly changed for the better (the degree of depression by Beck 20,3 ± 12,5 to 3,5 ± 2,2, the degree of depression by Shihan from 49,7 ± 18,1 to 7,0 ± 5 4, the quality of life for PA from 434 ± 182 to 167 ± 95) during 10 weeks of therapy.
If you want to buy Baclofen (Lioresal), consider that the drug tolerance in general is evaluated by both patients and clinicians as good. Side effects are observed only in the initial period of treatment.
The maximum content of the drug in the blood is noticed in 2-3 hours after oral administration, significantly decreasing after 6-8 hours. Therapeutic concentrations are quickly noticed in tissues and organs, often the same as in the blood. Particularly high concentrations are found in the liver, kidneys, lungs, bronchi, spleen, and lymph nodes. The drug is well absorbed by prostate gland, bone, and eye tissue.
Contraindications. The main contraindications are:
- violation of the normal functioning of the liver and jaundice;
- infectious mononucleosis, because the drug can cause skin rashes, which significantly affects the correct diagnosis.
The drug is dangerous to use during pregnancy, as it may not only harm the future baby, but also his mother.
Precautions. Care must be taken in when prescribing elderly patients, patients with angina, hypertension, epilepsy, and the insufficiency of the adrenal cortex and the pituitary gland, diabetes mellitus.
If there are any signs of hyperthyroidism during treatment, then it is recommended to reduce the daily dose or stop taking it for several days. With the disappearance of side effects the treatment can be gradually resumed. In children prescribing a high dose may violate the kidney function. It might cause a higher frequency of seizures in children with epilepsy.
During pregnancy and lactation therapy, the effects are still under medical supervision. The medicine is well studied, so there is no reason to presume that it has embryotoxic and teratogenic properties.
Interactions. When combined l with insulin may reduce the hypoglycemic action of the latter. The medicine increases the effect of anticoagulants – coumarin derivatives. Kolesteramin reduces the absorption of the medicine. When simultaneously taking with estrogens and estrogen oral contraceptives, the treatment may require higher doses of the drug.
Side effects. Cheap Baclofen (Lioresal) might have possible side effects: palpitations, fluctuations in blood pressure, respiratory disorders (hyperventilation, “asthma”, “insolvency breath”, “lump in the throat”), tension headaches, increased anxiety and inner tremors, fixation on the state of their health, decreased performance and a sense of helplessness, swoon (“darkening sight”), sleep disturbance (difficulty falling asleep, early awakening), “ringing in the ears.” One person might experience multiple side effects. When taken in recommended doses of the medicine there were no side effects observed. Higher doses may cause tachycardia, arrhythmia, angina, tremor, sleep disturbances, feeling of anxiety, sweating, and weight loss. In some cases, there might be temporary weight gain and hair loss.
Storage. The drug should be kept away from children and sunlight areas at temperature not exceeding 25 ° C. It is worth noting that the suspension may be appropriate to use for 7 days if stored in the refrigerator.
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