Bimatoprost 0.03% (bimatoprost ophthalmic)
General information. Bimatoprost 0.03% (also bimatoprost ophthalmic) is an active ingredient of a number of ophthalmic equipment (“Kareprost”, “Bimatov”, “Lyumigan”, “Xlash”, etc.) is used for the treatment of primary open-angle glaucoma, is now used for cosmetic purposes in the treatment of hypotrichosis of the eyelashes. Bimatoprost (bimatoprost ophthalmic) known as a substance, a part of air-conditioners for the growth of eyelashes. This component is present in all human cells and is a fatty acid having physiological activity. In other words, Bimatoprost 0.03% (bimatoprost ophthalmic) is involved in many vital processes: it stimulates cell growth, promotes the absorption of calcium in the body and affects the breakdown of fats.
First analogues bimatoprost 0.03% appeared in the 30s of the last century – they have been successfully used in medicine and is found in many medicines. Because of its uniqueness, Bimatoprost 0.03% (bimatoprost ophthalmic) is an expensive material – its value ranges from 1500 to 2500 U.S. dollars per 1 gram.
As an independent drug Bimatoprost (bimatoprost ophthalmic), which has established a production company Allergan, appeared on the American market in 2001. Doctors discharged patients Bimatoprost (bimatoprost ophthalmic) as drops in the treatment of glaucoma – increased intraocular pressure. After instillation into the eyes of a solution in which included Bimatoprost (bimatoprost ophthalmic), the state returns to normal patients. Incidentally, Allergan is known that she has been producing world-famous drug Botox.
Over time, patients have noticed that from drops bimatoprost (bimatoprost ophthalmic) lashes begin to grow better. Ophthalmologists U.S., studying this phenomenon came to the conclusion that the growth of eyelashes is very unusual side effect of the impact of drugs on the human body. And since, according to U.S. law permitted to designate one and the same drug against different diseases, doctors began recommending Bimatoprost (bimatoprost ophthalmic) and hypotrichosis – poor growth or loss of hair, eyebrows and eyelashes. It turns out that this medicine is officially received the status of funds for the growth of eyelashes in 2002.
Structure and Composition. Bimatoprost ophthalmic drops 0.03% for topical application in the vial 3ml plastic staffed applicator.
The main active ingredient of the drug: bimatoprost – 0.03 mg / ml
Additional ingredients: benzalkonium chloride , sodium chloride , disodium hydrogen phosphate , sodium , citric acid , distilled water . For possible pH adjustment with sodium hydroxide and / or hydrochloric acid. Wherein pH 6.8 – 7.8.
Indications. Substance bimatoprost is a structural analogue of prostaglandin. The exact mechanism of its action is unknown, but it is assumed that the growth and increase of eyelashes may occur by increasing the duration of the existence of the phase of the hair follicle, and the emergence of many new lashes.
Indications for use. Hypotrichosis (stunted) eyelashes or excessive loss.
Dosage. Despite the lack of laboratory studies of the interaction of the drug need to consider that may increase the effect of medicines that suppress the central nervous system (alcohol, sedatives, barbiturates, opium derivatives, general anesthetics).
Special instructions and precautions. Action of the drug is gradually over 2 months. It must be remembered that the effect of the use of bimatoprost is unstable, and in the event of termination of its use may return to the previous state of the eyelashes. Also, sometimes there is a difference in the length of the new lash their thickness, color intensity and direction of growth.
If you forget to put the drug in time, do not try to double the dose, the planned application of the drug to be held at the usual time the next night.
Not recommended to use the drug during pregnancy or breastfeeding due to a lack of clinical trial data.
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